Sex chromosome mosaicism in couples undergoing intracytoplasmic sperm injection

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Sex chromosome mosaicism in couples undergoing intracytoplasmic sperm injection.

BACKGROUND Several studies have shown an increased frequency of constitutional chromosome aberrations in male and female partners of couples examined prior to ICSI. We conducted a cohort study to determine whether there was an increase in numerical sex chromosome mosaicism among couples undergoing ICSI compared with fertile couples. METHODS Cytogenetic investigations were performed in 228 fem...

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Chromosome abnormalities in 447 couples undergoing intracytoplasmic sperm injection--prevalence, types, sex distribution and reproductive relevance.

Chromosomal abnormalities are thought to be a major contributor to the genetic risks of infertility treatment by intracytoplasmic sperm injection (ICSI). Apart from abnormalities arising de novo, abnormal karyotypes in pregnancies conceived through assisted reproductive technology may be directly derived from predisposing parental aberrations. In a prospective study we have analysed the chromos...

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The impact of endometriosis in couples undergoing intracytoplasmic sperm injection because of male infertility.

To assess the impact of endometriosis on intracytoplasmic sperm injection (ICSI) outcome, we have retrospectively evaluated 980 ICSI cycles, comparing the results of women with and without endometriosis. A total of 101 cycles was identified in which various degrees of endometriosis were involved, and in the remaining 879 cycles, male infertility was the only cause of infertility. Ejaculated spe...

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Success of intracytoplasmic sperm injection in couples with male and/or female chromosome aberrations.

This paper reports on results of intracytoplasmic sperm injection (ICSI) in patients in whom constitutional or secondary chromosome aberrations were detected in the male and/or female partner. Out of 434 couples treated by ICSI (590 cycles), 16 couples (3.7%) were affected by constitutional chromosome aberrations and 96 (22.1%) by secondary chromosome aberrations. Constitutional chromosome aber...

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Survey of Sex Ratio with Intracytoplasmic Sperm Injection

Abstract Introduction: In different studies worldwide, gender ratios derived from ICSI (Assisted reproductive techniques) have been reported differently. Objective: Evaluation of neonatal gender in ICSI women referred to Mehr Infertility Research Center of Rasht. Materials and Methods: In this descriptive-analytical study, the cases of infertile women referred to Mehr Infertility Research Ce...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2002

ISSN: 1460-2350

DOI: 10.1093/humrep/17.10.2552